Article
Functional genomics in the mouse.
Functional & integrative genomics - 1 Aug 2002
Perkins Archibald S
Abstract excerpt
The mouse is the premier genetic model organism for the study of human disease and development. With the recent advances in sequencing of the human and mouse genomes, there is strong interest now in large-scale approaches to decipher the function of mouse genes using various mutagenesis technologies. This review discusses what tools are currently available for manipulating and mutagenizing the mouse genome, such...
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