Article
Gene trap mutagenesis.
Handbook of experimental pharmacology - 1 Jan 2007
Abuin A, Hansen G M, Zambrowicz B
Abstract excerpt
Our ability to genetically manipulate the mouse has had a great impact on medical research over the last few decades. Mouse genetics has developed into a powerful tool for dissecting the genetic causes of human disease and identifying potential targets for pharmaceutical intervention. With the recent sequencing of the human and mouse genomes, a large number of novel genes have been identified whose function in...
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