Article
Electron-tomographic analysis of intraflagellar transport particle trains in situ.
The Journal of cell biology - 5 Oct 2009
Pigino Gaia, Geimer Stefan, Lanzavecchia Salvatore, Paccagnini Eugenio, Cantele Francesca, Diener Dennis R, Rosenbaum Joel L, Lupetti Pietro
Abstract excerpt
Intraflagellar transport (IFT) is the bidirectional movement of multipolypeptide particles between the ciliary membrane and the axonemal microtubules, and is required for the assembly, maintenance, and sensory function of cilia and flagella. In this paper, we present the first high-resolution ultrastructural analysis of trains of flagellar IFT particles, using transmission electron microscopy and...
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