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Article

Specific inhibition of proton pumping by the T315V mutation in the K channel of cytochrome ba3 from Thermus thermophilus.

Biochimica et biophysica acta. Bioenergetics - 1 Sept 2021

Siletsky Sergey A, Soulimane Tewfik, Belevich Ilya, Gennis Robert B, Wikström Mårten

Abstract excerpt

Cytochrome ba3 from Thermus thermophilus belongs to the B family of heme-copper oxidases and pumps protons across the membrane with an as yet unknown mechanism. The K channel of the A family heme-copper oxidases provides delivery of a substrate proton from the internal water phase to the binuclear heme-copper center (BNC) during the reductive phase of the catalytic cycle, while the D channel is responsible for...

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Identifiers

PMID: 34022199
DOI: 10.1016/j.bbabio.2021.148450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Specific inhibition of proton pumping by the T315V mutation in the K channel of cytochrome ba3 from Thermus thermophilus.PMID 34022199Read ↗

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