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Article

Single mutations that redirect internal proton transfer in the ba3 oxidase from Thermus thermophilus.

Biochemistry - 8 Oct 2013

Smirnova Irina, Chang Hsin-Yang, von Ballmoos Christoph, Ädelroth Pia, Gennis Robert B, Brzezinski Peter

Abstract excerpt

The ba3-type cytochrome c oxidase from Thermus thermophilus is a membrane-bound proton pump. Results from earlier studies have shown that with the aa3-type oxidases proton uptake to the catalytic site and "pump site" occurs simultaneously. However, with ba3 oxidase the pump site is loaded before proton transfer to the catalytic site because the proton transfer to the latter is slower than that with the aa3...

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Identifiers

PMID: 24004023
DOI: 10.1021/bi4008726
PMCID: PMC4282493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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