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Article

LRRK2 in Parkinson's disease: function in cells and neurodegeneration.

The FEBS journal - 1 Nov 2009

Webber Philip J, West Andrew B

Abstract excerpt

The detailed characterization of the function of leucine-rich repeat kinase 2 (LRRK2) may provide insight into the molecular basis of neurodegeneration in Parkinson's disease (PD) because mutations in LRRK2 cause a phenotype with strong overlap to typical late-onset disease and LRRK2 mutations are responsible for significant proportions of PD in some populations. The complexity of large multidomain protein...

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Identifiers

PMID: 19804415
DOI: 10.1111/j.1742-4658.2009.07342.x
PMCID: PMC3700730

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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