Article
On the road to leucine-rich repeat kinase 2 signalling: evidence from cellular and in vivo studies.
Neuro-Signals - 1 Jan 2011
Daniëls V, Baekelandt V, Taymans J-M
Abstract excerpt
Parkinson's disease (PD) is the most common neurodegenerative movement disorder. Although PD has long been considered a purely sporadic disorder, genetic research has revealed an underlying genetic cause in at least 10% of all PD cases. To date, mutations in the leucine-rich repeat kinase 2 (LRRK...
Topics
- Animals
- Apoptosis
- Cytoskeleton
- Dopamine
- Humans
- Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
- Mutation
- Parkinson Disease
- Protein Serine-Threonine Kinases
- Signal Transduction