Article
Targeting LRRK2 in Parkinson's disease: an update on recent developments.
Expert opinion on therapeutic targets - 1 Jun 2017
Chan Sharon L, Tan Eng-King
Abstract excerpt
INTRODUCTION: LRRK2 research has progressed significantly in recent years with more reports of LRRK2 interactors and the development of more specific and sophisticated LRRK2 kinase inhibitors. Identification of bone fide LRRK2 substrates will provide new therapeutic targets in LRRK2-linked Parkinson's disease (PD). Areas covered: This review aims to put current LRRK2 research into perspective. Beginning with...
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