Article
Analysis of cDNA coding MHC class II beta chain of the chimpanzee (Pan troglodytes).
Experimental animals - 1 Apr 2002
Hatta Yuki, Kanai Tomoko, Matsumoto Yoshitsugu, Kyuwa Shigeru, Hayasaka Ikuo, Yoshikawa Yasuhiro
Abstract excerpt
The chimpanzee (Pan troglodytes, Patr) is the closest zoological living relative of humans and shares approximately 98.6% genetic homology to human beings. Although major histocompatibility complex (MHC) plays a critical role in T cell-mediated immune responses in vertebrates, the information on Patr MHC remains at a relatively poor level. Therefore, we attempted to isolate Patr MHC class II genes and determine...
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