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Article

Full-length sequence analysis of the HLA-DRB1 locus suggests a recent origin of alleles.

Immunogenetics - 1 Apr 2007

von Salomé Jenny, Gyllensten Ulf, Bergström Tomas F

Abstract excerpt

The HLA region harbors some of the most polymorphic loci in the human genome. Among them is the class II locus HLA-DRB1, with more than 400 known alleles. The age of the polymorphism and the rate at which new alleles are generated at HLA loci has caused much controversy over the years. Previous studies have mostly been restricted to the 270 base pairs that constitute the second exon and represent the most...

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Source

Identifiers

PMID: 17345114
DOI: 10.1007/s00251-007-0196-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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