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Article

Genetic makeup of the DR region in rhesus macaques: gene content, transcripts, and pseudogenes.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2004

de Groot Nanine, Doxiadis Gaby G, De Groot Natasja G, Otting Nel, Heijmans Corrine, Rouweler Annemiek J M, Bontrop Ronald E

Abstract excerpt

In the human population, five major HLA-DRB haplotypes have been identified, whereas the situation in rhesus macaques (Macaca mulatta) is radically different. At least 30 Mamu-DRB region configurations, displaying polymorphism with regard to number and combination of DRB loci present per haplotype, have been characterized. Until now, Mamu-DRB region genes have been studied mainly by genomic sequencing of...

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PMID: 15128802
DOI: 10.4049/jimmunol.172.10.6152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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