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Article

Allelic based gene-gene interaction in case-control studies.

Human heredity - 1 Jan 2010

Jung Jeesun, Zhao Yiqiang

Abstract excerpt

In case-control studies identifying disease susceptibility loci, it has been shown that the interaction caused by multiple single nucleotide polymorphisms (SNPs) within a gene as well as by SNPs at unlinked genes plays an important role in influencing risk of a disease. A novel statistical approach is proposed to detect gene-gene interactions at the allelic level contributing to a disease trait. With a new...

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Identifiers

PMID: 19797905
DOI: 10.1159/000243150
PMCID: PMC2880732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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