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Article

An improved score test for genetic association studies.

Genetic epidemiology - 1 Jul 2011

Sha Qiuying, Zhang Zhaogong, Zhang Shuanglin

Abstract excerpt

Large-scale genome-wide association studies (GWAS) have become feasible recently because of the development of bead and chip technology. However, the success of GWAS partially depends on the statistical methods that are able to manage and analyze this sort of large-scale data. Currently, the commonly used tests for GWAS include the Cochran-Armitage trend test, the allelic χ(2) test, the genotypic χ(2) test, the...

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PMID: 21484862
DOI: 10.1002/gepi.20583

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