Article
Research on single nucleotide polymorphisms interaction detection from network perspective.
PloS one - 1 Jan 2015
Su Lingtao, Liu Guixia, Wang Han, Tian Yuan, Zhou Zhihui, Han Liang, Yan Lun
Abstract excerpt
Single Nucleotide Polymorphisms (SNPs) found in Genome-Wide Association Study (GWAS) mainly influence the susceptibility of complex diseases, but they still could not comprehensively explain the relationships between mutations and diseases. Interactions between SNPs are considered so important for deeply understanding of those relationships that several strategies have been proposed to explore such interactions....
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