Article
Evidence for Dicer-dependent RNA interference in the industrial penicillin producer Penicillium chrysogenum.
Microbiology (Reading, England) - 1 Dec 2009
Janus Danielle, Hoff Birgit, Kück Ulrich
Abstract excerpt
RNA interference (RNAi) is a sequence-specific post-transcriptional gene silencing system that downregulates target gene expression. Here, we provide several lines of evidence for RNA silencing in the industrial beta-lactam antibiotic producer Penicillium chrysogenum using the DsRed reporter gene under the control of the constitutive trpC promoter or the inducible xylP promoter. The functional RNAi system was...
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