Article
Mutants defective in a Mucor circinelloides dicer-like gene are not compromised in siRNA silencing but display developmental defects.
Fungal genetics and biology : FG & B - 1 Jun 2007
Nicolás Francisco E, de Haro Juan P, Torres-Martínez Santiago, Ruiz-Vázquez Rosa M
Abstract excerpt
Dicer proteins are ribonuclease III enzymes that process double stranded RNA precursors into small RNAs categorized as small interfering RNAs (siRNAs) or microRNAs (miRNAs), which suppress gene expression through the RNA silencing mechanism. We have isolated a dicer-like gene (dcl-1) of Mucor circinelloides, the first gene of this family to be identified in zygomycetes. The dcl-1 mRNA occurred in multiple forms,...
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