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Article

Insertional inactivation and cloning of the wA gene of Aspergillus nidulans.

Genetics - 1 Sept 1990

Tilburn J, Roussel F, Scazzocchio C

Abstract excerpt

We describe examples of wA gene inactivation (resulting in white conidiospores) obtained during transformation of Aspergillus nidulans. One wA- transformant was obtained by transformation with a prn+ plasmid of a strain with green conidia (wA+) which was unable to catabolize L-proline (prn-). This transformant contains a very large number of plasmid copies integrated at a single site inseparable from the wA...

Topics

Aspergillus nidulans
Blotting, Southern
Cloning, Molecular
DNA Transposable Elements
Gene Expression Regulation, Fungal
Genes, Fungal
Phenotype
Plasmids
Proline
Repetitive Sequences, Nucleic Acid
Restriction Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transformation, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 2172077
DOI: 10.1093/genetics/126.1.81
PMCID: PMC1204139

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2172077-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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