Article
RGS7 and -11 complexes accelerate the ON-bipolar cell light response.
Investigative ophthalmology & visual science - 1 Feb 2010
Zhang Jianmei, Jeffrey Brett G, Morgans Catherine W, Burke Neal S, Haley Tammie L, Duvoisin Robert M, Brown R Lane
Abstract excerpt
PURPOSE: The retinal ON-bipolar cell (ON-BPC) light response is initiated upon deactivation of the metabotropic glutamate receptor mGluR6 and the G protein Go. G protein-based signaling cascades are typically accelerated by interaction of the G protein alpha subunit with a member of the regulator...
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