Article

A metabotropic glutamate receptor agonist enhances visual signal fidelity in a mouse model of retinitis pigmentosa

2024-04-30

Abstract excerpt

Many inherited retinal diseases target photoreceptors, which transduce light into a neural signal that is processed by the downstream visual system. As photoreceptors degenerate, physiological and morphological changes to retinal synapses and circuitry reduce sensitivity and increase noise, degrading visual signal fidelity. Here, we pharmacologically targeted the first synapse in the retina in an effort to reduce...

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Literature Corpus work: 91cdd95c-76b4-5e3c-8779-6d18fafe567a
DOI: 10.1101/2024.04.30.591881

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