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Article

Reduced expression of the nob8 gene does not normalize the distribution or function of mGluR6 in the mouse retina.

Molecular vision - 1 Jan 2019

Kinoshita Junzo, Hasan Nazarul, Bell Brent A, Peachey Neal S

Abstract excerpt

Purpose: The Grm6nob8 mouse carries a missense mutation in the Grm6 gene (p.Met66Leu), and exhibits a reduced b-wave of the electroretinogram (ERG), abnormal localization of metabotropic glutamate receptor 6 (mGluR6) to the depolarizing bipolar cell (DBC) soma, and a reduced level of mGluR6 at the DBC dendritic tips. Although the underlying mechanism remains unknown, one possible explanation is that DBCs cannot...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32025181
PMCID: PMC6982428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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