Article
Neural reprogramming in retinal degeneration.
Investigative ophthalmology & visual science - 1 Jul 2007
Marc Robert E, Jones Bryan W, Anderson James R, Kinard Krista, Marshak David W, Wilson John H, Wensel Theodore, Lucas Robert J
Abstract excerpt
PURPOSE: Early visual defects in degenerative diseases such as retinitis pigmentosa (RP) may arise from phased remodeling of the neural retina. The authors sought to explore the functional expression of ionotropic (iGluR) and group 3, type 6 metabotropic (mGluR6) glutamate receptors in late-stage photoreceptor degeneration. METHODS: Excitation mapping with organic cations and computational molecular phenotyping...
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