Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional redundancy of R7 RGS proteins in ON-bipolar cell dendrites.

Investigative ophthalmology & visual science - 1 Feb 2010

Chen Frank S, Shim Hoon, Morhardt Duncan, Dallman Rebecca, Krahn Elizabeth, McWhinney Ludine, Rao Anjali, Gold Stephen J, Chen Ching-Kang

Abstract excerpt

PURPOSE: In the Gbeta5(-/-) mouse, the electroretinogram (ERG) b-wave is absent, and the R7 subfamily of regulators of G protein signaling (RGS), which includes RGS6, -7, -9, and -11, is downregulated. Mutant mouse strains deficient in RGS7 or -11 were characterized, and the SG711 strain which is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dendrites
Share to Fluorescent Antibody Technique, Indirect
Share to GTP-Binding Protein beta Subunits

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTPase-Activating Proteins

Share to Photic Stimulation

Share to Retinal Rod Photoreceptor Cells

Share to RGS Proteins

Share to Vision, Ocular

Source

Open in PubMed Open full text

Identifiers

PMID: 19797210
DOI: 10.1167/iovs.09-4084
PMCID: PMC2868441

Genes

RGS7
ERG
RGS11
RGS6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19797210-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional redundancy of R7 RGS proteins in ON-bipolar cell dendrites.PMID 19797210Read ↗

RGS7 and -11 complexes accelerate the ON-bipolar cell light response.Semantic proximity Read ↗

Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13.Semantic proximity Read ↗

Identification of a new mutant allele, Grm6(nob7), for complete congenital stationary night blindness.Semantic proximity Read ↗

Comparisons of structural and functional abnormalities in mouse b-wave mutants.Semantic proximity Read ↗

A New Mouse Model for Complete Congenital Stationary Night Blindness Due to Gpr179 Deficiency.Semantic proximity Read ↗

Reduced expression of the nob8 gene does not normalize the distribution or function of mGluR6 in the mouse retina.Semantic proximity Read ↗

Restoration of mGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night BlindnessSemantic proximity Read ↗

Allelic variance between GRM6 mutants, Grm6nob3 and Grm6nob4 results in differences in retinal ganglion cell visual responses.Semantic proximity Read ↗

Subcellular localization of regulator of G protein signaling RGS7 complex in neurons and transfected cells.Semantic proximity Read ↗

Gβ5 prevents the RGS7-Gαo interaction through binding to a distinct Gγ-like domain found in RGS7 and other RGS proteinsSemantic proximity Read ↗

Substantial restoration of night vision in adult mice with congenital stationary night blindnessSemantic proximity Read ↗

GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.