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Article

Functional redundancy of R7 RGS proteins in ON-bipolar cell dendrites.

Investigative ophthalmology & visual science - 1 Feb 2010

Chen Frank S, Shim Hoon, Morhardt Duncan, Dallman Rebecca, Krahn Elizabeth, McWhinney Ludine, Rao Anjali, Gold Stephen J, Chen Ching-Kang

Abstract excerpt

PURPOSE: In the Gbeta5(-/-) mouse, the electroretinogram (ERG) b-wave is absent, and the R7 subfamily of regulators of G protein signaling (RGS), which includes RGS6, -7, -9, and -11, is downregulated. Mutant mouse strains deficient in RGS7 or -11 were characterized, and the SG711 strain which is deficient in both proteins was examined, to learn whether the loss of some of these RGS proteins causes the absence of...

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Source

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Identifiers

PMID: 19797210
DOI: 10.1167/iovs.09-4084
PMCID: PMC2868441

Genes

RGS7
ERG
RGS11
RGS6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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