Human Hox-4.2 and Drosophila deformed encode similar regulatory specificities in Drosophila embryos and larvae.

doi:10.1016/0092-8674(90)90500-e

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Article

Human Hox-4.2 and Drosophila deformed encode similar regulatory specificities in Drosophila embryos and larvae.

Cell - 30 Nov 1990

McGinnis N, Kuziora M A, McGinnis W

Abstract excerpt

Within the serial array of vertebrate homeobox genes in the Hox complexes, it is possible to define a subgroup that is structurally homologous to the Drosophila homeotic gene Deformed (Dfd). We wished to test whether a vertebrate Dfd-like protein could substitute for any of the regulatory functio...

Topics

Amino Acid Sequence
Animals
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Embryo, Nonmammalian
Eye
Gene Expression Regulation
Genes, Homeobox
Homeodomain Proteins
Humans
Larva
Molecular Sequence Data
Phenotype
Sequence Homology, Nucleic Acid

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