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Article

Functional analysis of the mouse homeobox gene HoxB9 in Drosophila development.

Mechanisms of development - 1 Aug 1993

Malicki J, Bogarad L D, Martin M M, Ruddle F H, McGinnis W

Abstract excerpt

Mammalian genomes contain clusters of homeobox genes (Hox-C, HOX-C) which are structurally similar to the homeotic genes of the Drosophila HOM complex. One method for assessing the functional similarity of particular Drosophila HOM and mammalian Hox genes is to test the ability of Hox genes to induce homeotic phenotypes when expressed in developing Drosophila. Here we describe such functional tests using mouse...

Topics

Amino Acid Sequence
Animals
Base Sequence
DNA, Complementary
Drosophila
Genes, Homeobox
Heat-Shock Proteins
Homeodomain Proteins
Larva
Mice
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Proteins

Transformation, Genetic

Source

Identifiers

PMID: 8105876
DOI: 10.1016/0925-4773(93)90003-g

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8105876-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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