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Article

A genetic screen of the Drosophila X chromosome for mutations that modify Deformed function.

Genetics - 1 Dec 1998

Florence B, McGinnis W

Abstract excerpt

We have screened the Drosophila X chromosome for genes whose dosage affects the function of the homeotic gene Deformed. One of these genes, extradenticle, encodes a homeodomain transcription factor that heterodimerizes with Deformed and other homeotic Hox proteins. Mutations in the nejire gene, which encodes a transcriptional adaptor protein belonging to the CBP/p300 family, also interact with Deformed. The other...

Topics

Animals
Drosophila
Drosophila Proteins
Female
Gene Expression Regulation, Developmental
Genes, Insect
Genetic Testing
Homeodomain Proteins
Male
Mutation
Phenotype
X Chromosome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9832527
DOI: 10.1093/genetics/150.4.1497
PMCID: PMC1460420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-9832527-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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