Article
A cap 'n' collar protein isoform contains a selective Hox repressor function.
Development (Cambridge, England) - 1 Nov 1998
McGinnis N, Ragnhildstveit E, Veraksa A, McGinnis W
Abstract excerpt
We have characterized a protein isoform (CncB) from the Drosophila cap 'n' collar locus that selectively represses cis-regulatory elements that are activated by the Hox protein Deformed. Of the three Cnc protein isoforms, CncB is expressed in a localized pattern in mandibular and labral cells of the head during mid-stages of embryogenesis. When CncB protein is absent or reduced, mandibular cells are homeotically...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
