Article
Ectopic expression from the Deformed gene triggers a dominant defect in Drosophila adult head development.
Developmental biology - 1 Sept 1990
Chadwick R, Jones B, Jack T, McGinnis W
Abstract excerpt
Drosophila adults carrying a dominant allele of the Deformed locus (DfdD) have a mutant phenotype in which lower eye and orbital structures of the adult head are eliminated. The molecular defect responsible for this dominant mutation is a large, transposon-flanked, fragment of DNA inserted downstream of the Deformed (Dfd) transcription unit. The downstream transposon-flanked insert causes the inappropriate...
Topics
- Animals
- Blotting, Northern
- DNA
- DNA Transposable Elements
- Drosophila
- Gene Expression Regulation
- Head
- Phenotype
- Restriction Mapping