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Article

Enhanced recombinant protein production in pyruvate kinase mutant of Bacillus subtilis.

Applied microbiology and biotechnology - 1 Feb 2010

Pan Zhiwei, Cunningham Drew S, Zhu Tao, Ye Kaimin, Koepsel Richard R, Domach Michael M, Ataai Mohammad M

Abstract excerpt

Previous work demonstrated that acetate production was substantially lower in pyruvate kinase (pyk) mutant of Bacillus subtilis. The significantly lower acetate production in the pyk mutant is hypothesized to have positive effect on recombinant protein production either by lifting the inhibitory...

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PMID: 19787348
DOI: 10.1007/s00253-009-2244-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19787348-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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