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Article

Molecular and Physiological Logics of the Pyruvate-Induced Response of a Novel Transporter in Bacillus subtilis.

mBio - 3 Oct 2017

Charbonnier Teddy, Le Coq Dominique, McGovern Stephen, Calabre Magali, Delumeau Olivier, Aymerich Stéphane, Jules Matthieu

Abstract excerpt

At the heart of central carbon metabolism, pyruvate is a pivotal metabolite in all living cells. Bacillus subtilis is able to excrete pyruvate as well as to use it as the sole carbon source. We herein reveal that ysbAB (renamed pftAB), the only operon specifically induced in pyruvate-grown B. subtilis cells, encodes a hetero-oligomeric membrane complex which operates as a facilitated transport system specific for...

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Identifiers

PMID: 28974613
DOI: 10.1128/mBio.00976-17
PMCID: PMC5626966

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