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Article

Gilles de la Tourette syndrome is not linked to D2-dopamine receptor.

Archives of general psychiatry - 1 Nov 1990

Gelernter J, Pakstis A J, Pauls D L, Kurlan R, Gancher S T, Civelli O, Grandy D, Kidd K K

Abstract excerpt

Gilles de la Tourette syndrome has an important genetic component; the pathophysiology of this disorder may involve the dopamine system. We tested a D2-dopamine receptor (locus DRD2, recognized by probe hD2G1) for genetic linkage with Gilles de la Tourette syndrome. Using a genetic linkage map of the region of DRD2 on the long arm of chromosome 11 and restriction fragment length polymorphism data from a total of...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 11
Genetic Linkage
Genetic Markers
Humans
Lod Score
Mutation
Pedigree
Polymorphism, Restriction Fragment Length
Receptors, Dopamine
Tourette Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1978653
DOI: 10.1001/archpsyc.1990.01810230089014

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1978653-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Gilles de la Tourette syndrome is not linked to D2-dopamine receptor.PMID 1978653Read ↗

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