Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gilles de la Tourette syndrome is not linked to D2-dopamine receptor.

Archives of general psychiatry - 1 Nov 1990

Gelernter J, Pakstis A J, Pauls D L, Kurlan R, Gancher S T, Civelli O, Grandy D, Kidd K K

Abstract excerpt

Gilles de la Tourette syndrome has an important genetic component; the pathophysiology of this disorder may involve the dopamine system. We tested a D2-dopamine receptor (locus DRD2, recognized by probe hD2G1) for genetic linkage with Gilles de la Tourette syndrome. Using a genetic linkage map of the region of DRD2 on the long arm of chromosome 11 and restriction fragment length polymorphism data from a total of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Genetic Markers

Share to Lod Score

Share to Mutation

Share to Pedigree

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1978653
DOI: 10.1001/archpsyc.1990.01810230089014

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gilles de la Tourette syndrome is not linked to D2-dopamine receptor.PMID 1978653Read ↗

Dopamine receptor D2 gene polymorphisms are associated in Taiwanese children with Tourette syndrome.Semantic proximity Read ↗

Association of a missense change in the D2 dopamine receptor with myoclonus dystoniaSemantic proximity Read ↗

Exclusion of linkage between schizophrenia and the D2 dopamine receptor gene region of chromosome 11q in 112 Irish multiplex families.Semantic proximity Read ↗

Detection and characterization of additional DNA polymorphisms in the dopamine D2 receptor gene.Semantic proximity Read ↗

Association of multiple DRD2 polymorphisms with anorexia nervosa.Semantic proximity Read ↗

Association of DRD2 variants and Gilles de la Tourette syndrome in a family-based sample from a South American population isolate.Semantic proximity Read ↗

DRD2 allele frequencies and linkage disequilibria, including the -141CIns/Del promoter polymorphism, in European-American, African-American, and Japanese subjects.Semantic proximity Read ↗

Linkage study of the dopamine D5 receptor gene and Gilles de la Tourette syndrome.Semantic proximity Read ↗

Genomic analysis and functional expression of canine dopamine D2 receptor.Semantic proximity Read ↗

The -141C Ins/Del polymorphism of the dopamine D2 receptor gene is not associated with either migraine or Parkinson's disease.Semantic proximity Read ↗

Evaluation of the genes for the adrenergic receptors alpha 2A and alpha 1C and Gilles de la Tourette Syndrome.Semantic proximity Read ↗

Polymorphisms of the dopamine receptor gene DRD2 and colorectal cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.