Article
Detection and characterization of additional DNA polymorphisms in the dopamine D2 receptor gene.
Genomics - 1 Jul 1991
Hauge X Y, Grandy D K, Eubanks J H, Evans G A, Civelli O, Litt M
Abstract excerpt
The gene encoding the dopamine D2 receptor (DRD2) has been suggested as a candidate gene for several mental disorders. We previously described the cloning and chromosomal mapping (to 11q22-q23) of a human DRD2 gene as well as its use for the detection of a two-allele TaqI RFLP with a minor allele frequency of 0.24, corresponding to a PIC of 0.30. Family linkage utilizing DRD2 would be facilitated if the PIC of...
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