Article
Detection and characterization of additional DNA polymorphisms in the dopamine D2 receptor gene.
Genomics - 1 Jul 1991
Hauge X Y, Grandy D K, Eubanks J H, Evans G A, Civelli O, Litt M
Abstract excerpt
The gene encoding the dopamine D2 receptor (DRD2) has been suggested as a candidate gene for several mental disorders. We previously described the cloning and chromosomal mapping (to 11q22-q23) of a human DRD2 gene as well as its use for the detection of a two-allele TaqI RFLP with a minor allele...
Topics
- Alleles
- Base Sequence
- Chromosomes, Human, Pair 11
- Deoxyribonucleases, Type II Site-Specific
- Genes
- Genetic Linkage
- Humans
- Mental Disorders
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length