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Article

Linkage study of the dopamine D5 receptor gene and Gilles de la Tourette syndrome.

American journal of medical genetics - 21 Feb 1997

Barr C L, Wigg K G, Zovko E, Sandor P, Tsui L C

Abstract excerpt

A defect in the dopamine system has been hypothesized as the etiological defect in Gilles de la Tourette syndrome (TS). In this report, we test the hypothesis that the dopamine D5 receptor locus (DRD5) is linked to the genetic susceptibility to TS in five families studied in Canada. We tested for linkage to the dopamine D5 receptor gene using a microsatellite polymorphism located in the same cosmid clone. Using...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9034008

Genes

DRD5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Linkage study of the dopamine D5 receptor gene and Gilles de la Tourette syndrome.PMID 9034008Read ↗

No evidence for a major gene effect of the dopamine D4 receptor gene in the susceptibility to Gilles de la Tourette syndrome in five Canadian families.Semantic proximity Read ↗

Genome scan of Tourette syndrome in a single large pedigree shows some support for linkage to regions of chromosomes 5, 10 and 13Semantic proximity Read ↗

Significant linkage for Tourette syndrome in a large French Canadian family.Semantic proximity Read ↗

Genome scan for linkage to Gilles de la Tourette syndrome.Semantic proximity Read ↗

Genome scan for Tourette disorder in affected-sibling-pair and multigenerational families.Semantic proximity Read ↗

Tourette syndrome and dopaminergic genes: a family-based association study in the French Canadian founder population.Semantic proximity Read ↗

Catechol-O-methyltransferase and Gilles de la Tourette syndrome.Semantic proximity Read ↗

Association analysis between Tourette's syndrome and dopamine D1 receptor gene in Taiwanese children.Semantic proximity Read ↗

Linkage analysis of Tourette syndrome in a large Utah pedigree.Semantic proximity Read ↗

Association study of the SLITRK5 gene and Tourette syndrome.Semantic proximity Read ↗

A large Italian family with Gilles de la Tourette syndrome: clinical study and analysis of the SLITRK1 gene.Semantic proximity Read ↗

Linkage disequilibrium between an allele at the dopamine D4 receptor locus and Tourette syndrome, by the transmission-disequilibrium test.Semantic proximity Read ↗

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