Article
Dopamine receptor D2 gene polymorphisms are associated in Taiwanese children with Tourette syndrome.
Pediatric neurology - 1 Oct 2005
Lee Cheng-Chun, Chou I-Ching, Tsai Chang-Hai, Wang Tso-Ren, Li Tsai-Chung, Tsai Fuu-Jen
Abstract excerpt
The pathophysiology of Tourette syndrome may involve the dopamine system. Dysfunction of the dopamine receptor D2 gene leads to many neuropsychiatric disorders. The objective of this study is to test the hypothesis that the dopamine receptor D2 gene may play a role in Tourette syndrome. A total of 151 children with Tourette syndrome and 183 normal control subjects were included in the study. Polymerase chain...
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