Article
Association of multiple DRD2 polymorphisms with anorexia nervosa.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Sept 2005
Bergen Andrew W, Yeager Meredith, Welch Robert A, Haque Kashif, Ganjei J Kelly, van den Bree Marianne B M, Mazzanti Chiara, Nardi Irma, Fichter Manfred M, Halmi Katherine A, Kaplan Allan S, Strober Michael, Treasure Janet, Woodside D Blake, Bulik Cynthia M, Bacanu Silviu-Alin, Devlin Bernie, Berrettini Wade H, Goldman David, Kaye Walter H
Abstract excerpt
To investigate whether the dopaminergic system plays a role in the etiology of anorexia nervosa (AN) via the dopamine D2 receptor, we investigated association and transmission disequilibrium at seven single-nucleotide polymorphisms (SNPs) spanning about 75 kbp of the gene DRD2. We studied 191 probands with a DSM-IV diagnosis of AN, 457 parents and affected relatives with a DSM-IV eating disorder diagnosis, and 98...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.