Article
Evaluation of the genes for the adrenergic receptors alpha 2A and alpha 1C and Gilles de la Tourette Syndrome.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 May 2003
Xu Chun, Ozbay Fatih, Wigg Karen, Shulman Rayzie, Tahir Eda, Yazgan Yanki, Sandor Paul, Barr Cathy L
Abstract excerpt
Gilles de la Tourette Syndrome (GTS) has long been known to be familial, and evidence from twin studies indicates that it has a substantial genetic component. Our genome scan of sibling pair families with GTS found evidence suggestive of linkage to several chromosomal locations. On the basis of these findings, we have begun to study additional markers in these regions, with some of the markers located in...
Topics
- Family Health
- Genetic Predisposition to Disease
- Genotype
- Humans
- Inheritance Patterns
- Linkage Disequilibrium
- Receptors, Adrenergic, alpha-1
- Receptors, Adrenergic, alpha-2
- Tourette Syndrome