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Article

Roles of mitophagy and the mitochondrial permeability transition in remodeling of cultured rat hepatocytes

16 Nov 2009

Abstract excerpt

In primary culture, hepatocytes dedifferentiate, and their cytoplasm undergoes remodeling. Here, our aim was to characterize changes of mitochondria during remodeling. Hepatocytes were cultured one to five days in complete serumcontaining Waymouth's medium. In rat hepatocytes loaded with MitoTracker Green (MTG), tetramethylrhodamine methylester (TMRM), and/or LysoTracker Red (LTR), confocal microscopy revealed...

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PMID: 19783904
DOI: 10.4161/auto.5.8.9825

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