Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Remodeling of Mitochondrial Plasticity: The Key Switch from NAFLD/NASH to HCC

17 Apr 2021

Abstract excerpt

Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and the third-leading cause of cancer-related mortality. Currently, the global burden of nonalcoholic fatty liver disease (NAFLD) has dramatically overcome both viral and alcohol hepatitis, thus becoming the main cause of HCC incidence. NAFLD pathogenesis is severely influenced by lifestyle and genetic predisposition. Mitochondria...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Endoplasmic Reticulum Stress and Disease
Share to Liver Disease Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33920670
DOI: 10.3390/ijms22084173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Remodeling of Mitochondrial Plasticity: The Key Switch from NAFLD/NASH to HCCPMID 33920670Read ↗

Remodeling of Mitochondrial Plasticity: The Key Switch from NAFLD/NASH to HCCSemantic proximity Read ↗

Mitochondrial dynamics and nonalcoholic fatty liver disease (NAFLD): new perspectives for a fairy-tale ending?Semantic proximity Read ↗

Hepatocyte Mitochondrial Dynamics and Bioenergetics in Obesity-Related Non-Alcoholic Fatty Liver DiseaseSemantic proximity Read ↗

Epigenetics and mitochondrial dysfunction insights into the impact of the progression of non‐alcoholic fatty liver diseaseSemantic proximity Read ↗

Mitochondrial dysfunction and liver disease: role, relevance, and potential for therapeutic modulationSemantic proximity Read ↗

Mitochondrial dynamics, quality control, and mtDNA in alcohol-associated liver disease and liver cancerSemantic proximity Read ↗

Mitochondrial Dysfunction Plays Central Role in Nonalcoholic Fatty Liver DiseaseSemantic proximity Read ↗

Thyroid Hormone and Mitochondrial Dysfunction: Therapeutic Implications for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)Semantic proximity Read ↗

Metabolic reprogramming and its clinical implication for liver cancerSemantic proximity Read ↗

Exploring the Multifaceted Landscape of MASLD: A Comprehensive Synthesis of Recent Studies, from Pathophysiology to Organoids and BeyondSemantic proximity Read ↗

Epidemiologic, Genetic, Pathogenic, Metabolic, Epigenetic Aspects Involved in NASH-HCC: Current Therapeutic StrategiesSemantic proximity Read ↗

Mitochondrial quality control in liver fibrosis: Epigenetic hallmarks and therapeutic strategiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.