Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional properties of hepatocytes in vitro are correlated with cell polarity maintenance

1 Dec 2016

Abstract excerpt

Exploring the cell biology of hepatocytes in vitro could be a powerful strategy to dissect the molecular mechanisms underlying the structure and function of the liver in vivo. However, this approach relies on appropriate in vitro cell culture systems that can recapitulate the cell biological and metabolic features of the hepatocytes in the liver whilst being accessible to experimental manipulations. Here, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endoplasmic Reticulum Stress and Disease
Share to Liver physiology and pathology
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27916608
DOI: 10.1016/j.yexcr.2016.11.027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional properties of hepatocytes in vitro are correlated with cell polarity maintenancePMID 27916608Read ↗

The unique polarity phenotype of hepatocytes.Semantic proximity Read ↗

Hepatocyte polarity.Semantic proximity Read ↗

Distinct dedifferentiation processes affect caveolin-1 expression in hepatocytesSemantic proximity Read ↗

Structural and functional hepatocyte polarity and liver disease.Semantic proximity Read ↗

Cytoskeleton of liver perisinusoidal cells (lipocytes) in normal and pathological conditions.Semantic proximity Read ↗

Matrix Stiffness Regulates Liver Sinusoidal Endothelial Cell Function Mimicking Responses in Fatty Liver DiseaseSemantic proximity Read ↗

Human Liver-Derived Extracellular Matrix for the Culture of Distinct Human Primary Liver CellsSemantic proximity Read ↗

Analysis of culture and RNA isolation methods for precision-cut liver slices from cirrhotic ratsSemantic proximity Read ↗

An improved polarized rat hepatoma hybrid cell line: generation and comparison with its hepatoma relatives and hepatocytes in vivoSemantic proximity Read ↗

Characterisation of a functional rat hepatocyte spheroid modelSemantic proximity Read ↗

Serum-Free, Long-Term Cultures of Human Hepatocytes: Maintenance of Cell Morphology, Transcription Factors, and Liver-Specific FunctionsSemantic proximity Read ↗

Extra collagen overlay prolongs the differentiated phenotype in sandwich-cultured rat hepatocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.