Autophagy regulates cytoplasmic remodeling during cell reprogramming in a zebrafish model of muscle regeneration

Abstract excerpt

Cell identity involves both selective gene activity and specialization of cytoplasmic architecture and protein machinery. Similarly, reprogramming differentiated cells requires both genetic program alterations and remodeling of the cellular architecture. While changes in genetic and epigenetic programs have been well documented in dedifferentiating cells, the pathways responsible for remodeling the cellular...

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