Article
Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice.
Neurobiology of disease - 1 Feb 2010
Grueninger Fiona, Bohrmann Bernd, Czech Christian, Ballard Theresa Maria, Frey Johann R, Weidensteiner Claudia, von Kienlin Markus, Ozmen Laurence
Abstract excerpt
Amyloid beta peptides and microtubule-associated protein Tau are misfolded and form aggregates in brains of Alzheimer's disease patients. To examine their specific roles in the pathogenesis of Alzheimer's disease and their relevance in neurodegenerative processes, we have created TauPS2APP triple...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
