Article
Characterization of a double (amyloid precursor protein-tau) transgenic: tau phosphorylation and aggregation.
Neuroscience - 1 Jan 2005
Pérez M, Ribe E, Rubio A, Lim F, Morán M A, Ramos P Gómez, Ferrer I, Isla M T G, Avila J
Abstract excerpt
A double transgenic mouse expressing the amyloid precursor protein, bearing the Swedish mutations, and expressing tau protein containing three of the mutations present in frontotemporal dementia linked to chromosome 17 (FTDP-17), has been characterized. In the double transgenic mouse an increase...
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