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Article

Different tau epitopes define Abeta42-mediated tau insolubility.

Biochemical and biophysical research communications - 2 Dec 2005

Pennanen Luis, Götz Jürgen

Abstract excerpt

Alzheimer's disease (AD) is characterized by extracellular beta-amyloid (Abeta(42))-containing plaques and intracellular neurofibrillary tangles. The latter are composed of hyperphosphorylated filamentous aggregates of the microtubule-associated protein tau. Previously we demonstrated pathological interactions between these two histopathological hallmarks using human SH-SY5Y neuroblastoma cells overexpressing...

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PMID: 16226718
DOI: 10.1016/j.bbrc.2005.09.168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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