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Article

Parallel increase in p70 kinase activation and tau phosphorylation (S262) with Abeta overproduction.

FEBS letters - 23 Jan 2008

Zhou Xin-Wen, Tanila Heikki, Pei Jin-Jing

Abstract excerpt

This study set out to search for a link between overproduction of Abeta and p70S6 kinase (p70S6K) phosphorylation/activation. Results showed that levels of p-p70S6K at T421/S424 and T389 are significantly increased in mouse N2a neuroblastoma cells carrying human APP with Swedish mutation (APPswe)...

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Source

Identifiers

PMID: 18068129
DOI: 10.1016/j.febslet.2007.11.078

Genes

APP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18068129-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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