Article
Association of a functional polymorphism of PTPN22 encoding a lymphoid protein phosphatase in bilateral Meniere's disease.
The Laryngoscope - 1 Jan 2010
Lopez-Escamez Jose A, Saenz-Lopez Pablo, Acosta Lourdes, Moreno Antonia, Gazquez Irene, Perez-Garrigues Herminio, Lopez-Nevot Alicia, Lopez-Nevot Miguel A
Abstract excerpt
OBJECTIVES/HYPOTHESIS: Bilateral Meniere's disease (BMD) is a severe disease that usually results in bilateral severe or profound sensorineural hearing loss and chronic disequilibrium with loss of vestibular function. We examined single nucleotide polymorphisms (SNPs) in the PTPN22 and CTLA4 genes in Caucasian patients with BMD to assess the possible association between these polymorphism and the predisposition...
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