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Article

Allelic variants in TLR10 gene may influence bilateral affectation and clinical course of Meniere's disease.

Immunogenetics - 1 May 2013

Requena Teresa, Gazquez Irene, Moreno Antonia, Batuecas Angel, Aran Ismael, Soto-Varela Andres, Santos-Perez Sofia, Perez Nicolas, Perez-Garrigues Herminio, Lopez-Nevot Alicia, Martin Eduardo, Sanz Ricardo, Perez Paz, Trinidad Gabriel, Alarcon-Riquelme Marta E, Teggi Roberto, Zagato Laura, Lopez-Nevot Miguel A, Lopez-Escamez Jose A

Abstract excerpt

Toll-like receptors trigger the innate immune response by activating various cell types such us macrophages and lymphocytes. We genotyped SNV of TLR3, TRL7, TLR8 and TLR10 in 863 Spanish and 150 Italian patients with Meniere's disease (MD) and 1,013 controls by using Taqman assays. Real-Time qPCR was used to measure the expression level of TLR10 in peripheral blood leukocytes. The overall dataset showed that the...

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Identifiers

PMID: 23370977
DOI: 10.1007/s00251-013-0683-z

Genes

TLR10
TLR3
TLR8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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