Article
High resolution transcriptome maps for wild-type and nonsense-mediated decay-defective Caenorhabditis elegans.
Genome biology - 1 Jan 2009
Ramani Arun K, Nelson Andrew C, Kapranov Philipp, Bell Ian, Gingeras Thomas R, Fraser Andrew G
Abstract excerpt
BACKGROUND: While many genome sequences are complete, transcriptomes are less well characterized. We used both genome-scale tiling arrays and massively parallel sequencing to map the Caenorhabditis elegans transcriptome across development. We utilized this framework to identify transcriptome changes in animals lacking the nonsense-mediated decay (NMD) pathway. RESULTS: We find that while the majority of...
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