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Article

Partial C antigen in sickle cell disease patients: clinical relevance and prevention of alloimmunization

22 Sept 2009

Abstract excerpt

BACKGROUND: Partial Rh antigens have been widely described in black individuals. Carriers are prone to immunization when exposed to the normal antigens. In sickle cell disease (SCD), patient alloimmunization is a major cause of transfusion failure. The potential of individuals with partial C antigen to make anti-C has not been investigated. We sought partial C status and anti-C production in a cohort of SCD...

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PMID: 19778340
DOI: 10.1111/j.1537-2995.2009.02382.x

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