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Article

Cloning of an aroF allele encoding a tyrosine-insensitive 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.

Journal of bacteriology - 1 Nov 1990

Weaver L M, Herrmann K M

Abstract excerpt

In Escherichia coli, genes aroF+, aroG+, and aroH+ encode isoenzymes of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthases that are feedback inhibited by tyrosine, phenylalanine, and tryptophan, respectively. A single base pair change in aroF causes a Pro-148-to-Leu-148 substitution and results in a tyrosine-insensitive enzyme.

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Source

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Identifiers

PMID: 1977738
DOI: 10.1128/jb.172.11.6581-6584.1990
PMCID: PMC526849

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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