Article
Corynebacterium glutamicum contains 3-deoxy-D-arabino-heptulosonate 7-phosphate synthases that display novel biochemical features.
Applied and environmental microbiology - 1 Sept 2008
Liu Ya-Jun, Li Pan-Pan, Zhao Ke-Xin, Wang Bao-Jun, Jiang Cheng-Ying, Drake Harold L, Liu Shuang-Jiang
Abstract excerpt
3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase (EC 2.5.1.54) catalyzes the first step of the shikimate pathway that finally leads to the biosynthesis of aromatic amino acids phenylalanine (Phe), tryptophan (Trp), and tyrosine (Tyr). In Corynebacterium glutamicum ATCC 13032, two chromosomal genes, NCgl0950 (aroF) and NCgl2098 (aroG), were located that encode two putative DAHP synthases. The deletion...
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