Article
Molecular modeling and functional analysis of the AtoS-AtoC two-component signal transduction system of Escherichia coli.
Biochimica et biophysica acta - 1 Aug 2007
Grigoroudis A I, Panagiotidis C A, Lioliou E E, Vlassi M, Kyriakidis D A
Abstract excerpt
The AtoS-AtoC two-component signal transduction system positively regulates the expression of the atoDAEB operon in Escherichia coli. Upon acetoacetate induction, AtoS sensor kinase autophosphorylates and subsequently phosphorylates, thereby activating, the response regulator AtoC. In a previous work we have shown that AtoC is phosphorylated at both aspartate 55 and histidine73. In this study, based on known...
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